Interlocking Stabilised Soil Block (ISSB) technology has been gaining recognition, particularly in East Africa. This material and method of construction has the advantages of low cost and minimal environmental impact, while providing comparable quality to conventional fired brick construction. With a growing number of organisations using the technology there is a need to improve communication and knowledge-sharing, to quantify and verify the benefits, and to develop efficient approaches for its promotion and adoption. The purpose of this publication is to promote the use of ISSB by sharing some case studies of successful adoption and adaptation to local contexts. It also highlights some of the challenges faced in developing and promoting the technology with some key lessons learned from projects in northern Uganda. This document provides stakeholders interested in the sustainable development of human settlements with a reference tool for an innovative construction method in practice.